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Model Details

Patient Information for Model: BCM-15046

Patient Information

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Clinical Information at Collection

Clinical Biomarkers/Mutations at Collection

Pathology Information at Collection

Model Information for Model: BCM-15046

Model Details - Initial Implantation of Patient Tissue

Biomarkers & Mutations

Model Details - Acceptable Conditions for Passaging

Mutations (Cancer Gene Census List)

GeneFilter by Gene	ChrFilter by Chr	Start	End	Ref	Alt	cDNA Change	Codon Change	Protein Change	TVAF	Gene Mutation Freq.	Site Mutation Freq.	Most Severe Effect	All Effects	Mutation Impact	Transcript ID	ClinVar Clinical Significance	COSMIC ID	gnomAD Non-Cancer AF	dbSNP ID	Gene Mutation Freq.	Site Mutation Freq.	Transcript ID	ClinVar Clinical Significance	COSMIC ID	dbSNP ID
AKAP9	chr7	92097327	92097330	TAGA	T	c.10373_10375del	AGA/-	p.R3458del	0.316	50	3	In-frame Deletion	In-frame Deletion	MODERATE	ENST00000356239.8				rs757087367	50	3	ENST00000356239.8			rs757087367
AR	chrX	67546514	67546514	T	TGGC	c.1418_1420dup	-/GGC	p.G473dup	0.639	48	8	In-frame Insertion	In-frame Insertion	MODERATE	ENST00000374690.9		COSV104687717			48	8	ENST00000374690.9		COSV104687717
ARID1A	chr1	26696849	26696849	G	A	c.446G>A	gGc/gAc	p.G149D	0.803	19	3	Missense Variant	Missense Variant	MODERATE	ENST00000324856.13	Uncertain_significance	COSV61376273		rs2080267760	19	3	ENST00000324856.13	Uncertain_significance	COSV61376273	rs2080267760
ATRX	chrX	77682471	77682471	C	G	c.2785G>C	Gag/Cag	p.E929Q	0.425	59	56	Missense Variant	Missense Variant	MODERATE	ENST00000373344.10	Benign			rs3088074	59	56	ENST00000373344.10	Benign		rs3088074
BARD1	chr2	214767531	214767532	CA	TG	c.1518_1519inv	caTGtg/caCAtg	p.V507M	0.653	34	24	Missense Variant	Missense Variant	MODERATE	ENST00000260947.9		COSV105837301		rs386654966	34	24	ENST00000260947.9		COSV105837301	rs386654966
BAZ1A	chr14	34800248	34800248	C	G	c.1104G>C	gaG/gaC	p.E368D	0.15	9	2	Missense Variant	Missense Variant	MODERATE	ENST00000360310.6				rs1773618060	9	2	ENST00000360310.6			rs1773618060
BCL6	chr3	187728428	187728428	T	G	c.1472A>C	cAc/cCc	p.H491P	0.249	2	1	Missense Variant	Missense Variant	MODERATE	ENST00000406870.7			0.000008562960	rs748627517	2	1	ENST00000406870.7			rs748627517
BCORL1	chrX	130013265	130013265	C	T	c.493C>T	Cgg/Tgg	p.R165W	0.194	11	2	Missense Variant	Missense Variant	MODERATE	ENST00000540052.5			0.000005804670	rs185537912	11	2	ENST00000540052.5			rs185537912
BCR	chr22	23182000	23182000	C	T	c.1040C>T	tCt/tTt	p.S347F	0.104	7	2	Missense Variant	Missense Variant	MODERATE	ENST00000305877.13					7	2	ENST00000305877.13
BCR	chr22	23314599	23314599	C	G	c.3611C>G	gCc/gGc	p.A1204G	0.05	7	2	Missense Variant	Missense Variant	MODERATE	ENST00000305877.13		COSV59925974	0.000060068300	rs56265970	7	2	ENST00000305877.13		COSV59925974	rs56265970
BIRC6	chr2	32515477	32515480	ATTC	A	c.11059_11061del	aTTCtt/att	p.L3687del	0.135	15	3	In-frame Deletion	In-frame Deletion	MODERATE	ENST00000421745.6					15	3	ENST00000421745.6
BRCA1	chr17	43091983	43091983	T	C	c.3548A>G	aAa/aGa	p.K1183R	0.047	19	1	Missense Variant	Missense Variant	MODERATE	ENST00000357654.9	Benign	COSV58784397	0.354676000000	rs16942	19	1	ENST00000357654.9	Benign	COSV58784397	rs16942
CDK12	chr17	39462615	39462618	GAGA	G	c.548_550del	gAGAag/gag	p.K183del	0.9	8	3	In-frame Deletion	In-frame Deletion	MODERATE	ENST00000447079.6					8	3	ENST00000447079.6
CHD2	chr15	92992958	92992958	G	C	c.3555G>C	atG/atC	p.M1185I	0.254	5	1	Missense Variant	Missense Variant	MODERATE	ENST00000394196.9					5	1	ENST00000394196.9
CIC	chr19	42291340	42291340	C	T	c.2572C>T	Ccc/Tcc	p.P858S	0.91	11	3	Missense Variant	Missense Variant	MODERATE	ENST00000575354.6		COSV99360636	0.000175355000	rs139895527	11	3	ENST00000575354.6		COSV99360636	rs139895527

CNV

Histology Information for Model: BCM-15046