The Patient-Derived Xenograft and Advanced In Vivo Models (PDX-AIM) Core of Baylor College of Medicine is divided into two independent functional units, a PDX Development Unit created to facilitate establishment and use of PDX models using immunocompromised mice as hosts, and an Advanced In Vivo Models Unit created to facilitate establishment and use of patient material grown on the chorioallantoic membrane of the chicken egg (CAM-PDX).
This PDX Portal is designed to allow investigators to browse the various organ site-specific PDX collections being developed at the College and to identify PDX models and approaches to address individual research questions.The Core is supported by institutional funding from both the Advanced Technology Cores and the Dan L. Duncan Cancer Center (P30 Cancer Center Support Grant NCI-CA125123). It is also supported by a Core Facility grant from the Cancer Prevention and Research Institute of Texas (CPRIT Core Facilities Support Grant RP170691).