The Patient-Derived Xenograft (PDX) Core of Baylor College of Medicine was created to facilitate establishment and use of PDX models using immunocompromised mice as hosts. The PDX Core also provides computational and bioinformatics infrastructure to support large scale, multi-omics data processing to mine patient and PDX associated data for identification of models for preclinical therapeutic studies.

This PDX Portal is designed to allow investigators to browse the various organ site-specific PDX collections being developed at the College and to identify PDX models and approaches to address individual research questions. The Core is supported by institutional funding from both the Advanced Technology Cores and the Dan L Duncan Cancer Center (P30 Cancer Center Support Grant NCI-CA125123). It is also supported by a Core Facility grant from the Cancer Prevention and Research Institute of Texas (Patient-derived Xenograft (PDX) Core Facility of Texas RP220646).