PDX INSIGHTS
PIONEERING CANCER RESEARCH
Model Details

Patient Information for Model: TCH-AML002

Model Contact
Model: TCH-AML002
Model Contact: Michele Redell
Institution: TCH Leukemia PDX Program
Email: mlredell@texaschildrens.org

Patient Information
Clinical Timeline


Clinical Information at Collection
Clinical Biomarkers/Mutations

Model Information for Model: TCH-AML002

Model Details - Initial Implantation of Patient Tissue
Mutations (Cancer Gene Census List)
Mutation data is currently not available.

CNV
There are no omics data for this model.


Histology Information for Model: TCH-AML002
There are no histology images for this model.













Metastasis Information for Model: TCH-AML002
 
Patient
PDX
Abdomen
BM
Central Nervous System
Face
Gingiva
Kidney
Kidneys
L cheek
Leg
Liver
Lymph node
Orbital chloroma
PB
Pancreas
Periorbital
Retinas
Skin
Skull base
Spine
Spleen
Stomach
Tail
Temporal bone
Testis
Tongue
periorbital chloroma
sacrum

Patient Treatment Information for Model: TCH-AML002

Event IdTreatmentTreatment SettingAge at StartAge at EndDurationClinical ResponseMeasurable Residual Disease
10Cytarabine/IdarubicinDe Novo20.06UnknownInduction Failure
15Cytarabine/FludarabineRefractory20.25UnknownResidual Disease
20clo/topotecan/vinorelbine/thiotepaRefractory20.37UnknownResidual Disease
25azacitidine/venetoclaxRefractory20.54Unknown
30venetoclaxRefractory20.66UnknownRemission.16%
50decitabine/venetoclax then DLIRelapse21.3UnknownRelapse14%
60decitabine/venetoclax then DLIRelapse21.4UnknownRelapse4%













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