PDX Portal

Model Details

Patient Information for Model: TCH-AML001

Model Contact

Model: TCH-AML001
Model Contact: Michele Redell
Institution: TCH Leukemia PDX Program
Email: mlredell@texaschildrens.org

Patient Information

Clinical Timeline

Clinical Information at Collection

Clinical Biomarkers/Mutations

Model Information for Model: TCH-AML001

Model Details - Initial Implantation of Patient Tissue

Mutations (Cancer Gene Census List)

Mutation data is currently not available.

CNV

There are no omics data for this model.

Histology Information for Model: TCH-AML001

There are no histology images for this model.

Metastasis Information for Model: TCH-AML001

Patient

PDX

Abdomen

Central Nervous System

Face

Gingiva

Kidney

Kidneys

L cheek

Leg

Liver

Lymph node

Orbital chloroma

Pancreas

Periorbital

Retinas

Skin

Skull base

Spine

Spleen

Stomach

Tail

Temporal bone

Testis

Tongue

periorbital chloroma

sacrum

Patient Treatment Information for Model: TCH-AML001

Event Id	Treatment	Treatment Setting	Age at Start	Age at End	Duration	Clinical Response	CNS Response
10	AAML1031 ADE10, ADE8, AE	De Novo	1.34	1.42	29 days	Complete Remission	CSF Negative
30	HDAC/Erwinia	Relapse	1.59		Unknown	Refractory
40	Ida/2CDA/dexamethasone	Relapse	1.67		Unknown	Morphologic Complete Response	CSF Negative
55	Multiple intensive regimens	Relapse	1.84		Unknown	Refractory	CSF Positive
70	MTX/VCR/PEG-asp	Palliative	1.99		Unknown	Refractory	CSF Positive