Model Details

Patient Information for Model: BCM-15057

Patient Information
Clinical Timeline

Color Keys:
 
 Positive
 
 Negative
 
 N/A

Clinical Information at Collection
Clinical Biomarkers/Mutations at Collection
Pathology Information at Collection

Model Information for Model: BCM-15057

Biomarkers & Mutations
Model Details
Mutations (Cancer Gene Census List)

The number of models in this collection with mutations in the listed gene
The number of models in this collection with mutations at the listed site
GeneChrStartEndRefAltVariant TypecDNA ChangeCodon ChangeProtein ChangeTVAF Gene Mutation Freq. Site Mutation Freq.Gene Mutation Freq.Site Mutation Freq.
ACSL32223773638223773638GAMissense Variantc.148G>AGaa/Aaap.E50K0.4582121
ACVR12158637104158637104GAMissense Variantc.76C>TCcc/Tccp.P26S0.4643131
ARHGEF10819050481905048CAMissense Variantc.3540C>AgaC/gaAp.D1180E1.0281281
ATM11108175462108175462GAMissense Variantc.5557G>AGat/Aatp.D1853N1.031123112
ATR3142178144142178144CTMissense Variantc.7274G>AcGa/cAap.R2425Q0.36830163016
CASP82202122956202122956TCMissense Variantc.2T>CaTg/aCgp.M1T0.524153153
CIITA161100150411001504GAMissense Variantc.2155G>AGcc/Accp.A719T1.0181181
CNTRL9123907175123907175CTMissense Variantc.1450C>TCtc/Ttcp.L484F0.534321321
CPEB3109399939293999392GAMissense Variantc.716C>TtCg/tTgp.S239L0.5435151
CRTC1191887625818876258GAMissense Variantc.931G>AGtc/Atcp.V311I0.5017575
CUX17101755010101755010CGNonsense Mutationc.548C>GtCa/tGap.S183*0.457121121
DNM2191093983210939832CTMissense Variantc.2167C>TCat/Tatp.H723Y0.464232232
EGFR75522925555229255GAMissense Variantc.761G>AaGg/aAgp.R254K0.44939253925
EP300224157438341574383ACMissense Variantc.6668A>CcAg/cCgp.Q2223P0.47382382
ERC11211372171137217AGMissense Variantc.148A>GAgt/Ggtp.S50G0.328129129
CNV


Histology Information for Model: BCM-15057

Patient

PDX

H&E

ER

PR

HER2


Metastasis Information for Model: BCM-15057
 
Patient
PDX
Abdomen
Anterosuperior mediastinum
Bone
Brain
CTC
Chest
Chest wall
Contralateral breast
Fallopian tubes
Hip
Kidney
Leg bone
Liver
Lung
Lymph Node
Mediastinum
Neck
Other
Ovary
Pancreas
Paratracheal adenopathy
Pericardium
Peritoneal cavity
Peritoneum
Pleura
Pleural Cavitiy
Pleural effusion
Posterior cervical nodes
SVC node
Skin
Thymus

Patient Treatment Information for Model: BCM-15057

Event IdTreatmentTreatment SettingAge at StartAge at EndDurationClinical ResponsePathologic ResponseReason Stopped
8AnastrazoleNeoadjuvant80.1681.14358 daysNot ReportedNot ReportedTreatment Completed
17PaclitaxelAdjuvant81.2581.5195 daysNot ReportedNot ApplicableTreatment Completed
19Radiation Therapy (RT)Adjuvant81.5481.6747 daysNot ReportedNot ApplicableTreatment Completed
22ExemestaneAdjuvant81.782.58321 daysNo Response (NR)Not ApplicableDisease Progression












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