Model Details

Patient Information for Model: BCM-15029

Patient Information
Clinical Timeline

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Clinical Information at Collection
Clinical Biomarkers/Mutations at Collection
Pathology Information at Collection

Model Information for Model: BCM-15029

Biomarkers & Mutations
Model Details
Mutations (Cancer Gene Census List)

The number of models in this collection with mutations in the listed gene
The number of models in this collection with mutations at the listed site
GeneChrStartEndRefAltcDNA ChangeCodon ChangeProtein ChangeTVAF Gene Mutation Freq. Site Mutation Freq.Most Severe EffectAll EffectsMutation ImpactTranscript IDClinVar Clinical SignificanceCOSMIC IDgnomAD Non-Cancer AFdbSNP IDGene Mutation Freq.Site Mutation Freq.Transcript IDClinVar Clinical SignificanceCOSMIC IDdbSNP ID
ACSL6chr5132011827132011827GA0.9944724Upstream Gene Variantupstream_gene_variantMODIFIERNM_001009185.2


rs4705908
4724NM_001009185.2rs4705908
ACSL6chr5132011827132011827GA0.9944724Intragenic Variantintragenic_variantMODIFIER


rs4705908
4724rs4705908
AFF1chr48713577387135773AG0.97880803' UTR variant3_prime_UTR_variantMODIFIERNM_001166693.2


rs342464
8080NM_001166693.2rs342464
AFF4chr5132873472132873472ATCACA0.932114Downstream Gene Variantdownstream_gene_variantMODIFIERNM_014423.3


rs142228782
2114NM_014423.3rs142228782
AKAP9chr79194097691940976GC0.32568645' UTR variant5_prime_UTR_variantMODIFIERNM_005751.4


rs4727267
6864NM_005751.4rs4727267
AKT2chr194023381440233814GT0.48850473' UTR variant3_prime_UTR_variantMODIFIERNM_001626.5


rs2304186
5047NM_001626.5rs2304186
ALKchr22919315929193163CCATTG0.62140333' UTR variant3_prime_UTR_variantMODIFIERNM_004304.4


rs397706189
4033NM_004304.4rs397706189
APOBEC3Bchr223898211638982116TG0.9372623Upstream Gene Variantupstream_gene_variantMODIFIERNM_004900.4


rs2267401
2623NM_004900.4rs2267401
ARHGEF10Lchr11769750217697503GGC0.98277773' UTR variant3_prime_UTR_variantMODIFIERNM_018125.3


rs3835471
7777NM_018125.3rs3835471
ARID1Bchr6157190043157190043GCc.3695G>CaGt/aCtp.Ser1232Thr0.953164Missense Variantmissense_variantMODERATENM_020732.3



164NM_020732.3
ASXL1chr203243742832437428TC0.88949433' UTR variant3_prime_UTR_variantMODIFIERNM_015338.5


rs2295763
4943NM_015338.5rs2295763
ATICchr2215311925215311925AG0.9977974Upstream Gene Variantupstream_gene_variantMODIFIERNM_004044.6


rs78631308
7974NM_004044.6rs78631308
ATICchr2215312084215312084TG0.96879235' UTR variant5_prime_UTR_variantMODIFIERNM_004044.6


rs4535042
7923NM_004044.6rs4535042
ATP1A1chr1116406090116406090GA0.54948Downstream Gene Variantdownstream_gene_variantMODIFIERNM_000701.7


rs850610
4948NM_000701.7rs850610
ATRchr3142447814142447814GA0.545114Downstream Gene Variantdownstream_gene_variantMODIFIERNM_001184.3



114NM_001184.3
CNV


Histology Information for Model: BCM-15029

Patient

PDX

ER

PR

HER2


Metastasis Information for Model: BCM-15029
 
Patient
PDX
Abdomen
Anterosuperior mediastinum
Bone
Brain
CTC
Chest
Chest wall
Contralateral breast
Fallopian tubes
Hip
Kidney
Leg bone
Liver
Lung
Lymph Node
Mediastinum
Neck
Other
Ovary
Pancreas
Paratracheal adenopathy
Pericardium
Peritoneal cavity
Peritoneum
Pleura
Pleural Cavitiy
Pleural effusion
Posterior cervical nodes
SVC node
Skin
Thymus

Patient Treatment Information for Model: BCM-15029

Event IdTreatmentTreatment SettingAge at StartAge at EndDurationClinical ResponsePathologic ResponseReason Stopped
12[Radiation Therapy (RT), Doxorubicin, Cyclophosphamide]Adjuvant46.9347.59241 daysNot ReportedNot ReportedTreatment Completed
22[Carboplatin, Docetaxel]Neoadjuvant63.0963.3284 daysPartial ResponseSide Effects












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