Model Details

Patient Information for Model: BCM-15008

Patient Information
Clinical Timeline

Color Keys:
 
 Positive
 
 Negative
 
 N/A

Clinical Information at Collection
Clinical Biomarkers/Mutations at Collection
Pathology Information at Collection

Model Information for Model: BCM-15008

Biomarkers & Mutations
Model Details
Mutations (Cancer Gene Census List)

The number of models in this collection with mutations in the listed gene
The number of models in this collection with mutations at the listed site
GeneChrStartEndRefAltVariant TypecDNA ChangeCodon ChangeProtein ChangeTVAF Gene Mutation Freq. Site Mutation Freq.Gene Mutation Freq.Site Mutation Freq.
AKAP979170889891708898AGMissense Variantc.7451A>GaAa/aGap.K2484R0.436259259
ANK184154367541543675GAMissense Variantc.4385C>TgCa/gTap.A1462V0.218164164
ARX6676515866765167TGCAGCAGCATDeletionc.171_179delp.Q78_Q80del1.042114211
ARHGEF10818575911857591GAMissense Variantc.1984G>AGtt/Attp.V662I0.508284284
ARHGEF1211120340060120340060ATMissense Variantc.2861A>TtAt/tTtp.Y954F0.928139139
AXIN116396911396911GAMissense Variantc.115C>TCcc/Tccp.P39S0.9465252
BCL1018573337485733374CTMissense Variantc.605G>AgGa/gAap.G202E0.283119119
CBFA2T3168895159488951594CTMissense Variantc.719G>AcGc/cAcp.R240H0.366132132
CBLC194529680645296806CTMissense Variantc.1075C>TCac/Tacp.H359Y0.439494
CDH11166501613765016137GCMissense Variantc.689C>GcCg/cGgp.P230R0.5518282
CTNND1115756401157564011CTMissense Variantc.200C>TtCa/tTap.S67L0.3996161
DDR21162724986162724986AGMissense Variantc.458A>GaAg/aGgp.K153R0.4029191
DDR21162740121162740121GAMissense Variantc.1323G>AatG/atAp.M441I0.549595
EZH27148525904148525904CGMissense Variantc.436G>CGac/Cacp.D146H0.96211101110
FANCC99791230797912307TAMissense Variantc.584A>TgAt/gTtp.D195V0.917272
CNV


Histology Information for Model: BCM-15008

Patient

PDX

ER

PR

HER2


Metastasis Information for Model: BCM-15008
 
Patient
PDX
Abdomen
Anterosuperior mediastinum
Bone
Brain
CTC
Chest
Chest wall
Contralateral breast
Fallopian tubes
Hip
Kidney
Leg bone
Liver
Lung
Lymph Node
Mediastinum
Neck
Other
Ovary
Pancreas
Paratracheal adenopathy
Pericardium
Peritoneal cavity
Peritoneum
Pleura
Pleural Cavitiy
Pleural effusion
Posterior cervical nodes
SVC node
Skin
Thymus

Patient Treatment Information for Model: BCM-15008

Event IdTreatmentTreatment SettingAge at StartAge at EndDurationReason Stopped
12[Doxorubicin, Cyclophosphamide]Adjuvant64.164.1UnknownSide Effects
14[Docetaxel, Cyclophosphamide]Adjuvant64.1164.45124 daysDisease Progression
22[Gemcitabine, Cisplatin]Recurrent/Metastatic64.5464.54UnknownDisease Progression
26[Radiation Therapy (RT), Cisplatin]Recurrent/Metastatic64.5964.6522 daysDisease Progression












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