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Breast
BCM-15008
Model Details
Patient
PDX Model
Histology
Metastasis
Patient Treatment
Patient Information for Model: BCM-15008
Patient Information
Clinical Timeline
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N/A
Clinical Information at Collection
Clinical Biomarkers/Mutations at Collection
Pathology Information at Collection
Model Information for Model: BCM-15008
Biomarkers & Mutations
Model Details
Mutations (Cancer Gene Census List)
Download Complete Mutation List
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The number of models in this collection with mutations in the listed gene
The number of models in this collection with mutations at the listed site
Total mutations showing: 61
F
P
1
2
3
4
5
N
E
Rows Per Page
10
15
25
50
Download
Gene
Filter by Gene
Chr
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Start
End
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Alt
Variant Type
Filter by Variant Type
cDNA Change
Codon Change
Protein Change
TVAF
Gene Mutation Freq.
Site Mutation Freq.
Gene Mutation Freq.
Site Mutation Freq.
AKAP9
7
91708898
91708898
A
G
Missense Variant
c.7451A>G
aAa/aGa
p.K2484R
0.436
25
9
25
9
ANK1
8
41543675
41543675
G
A
Missense Variant
c.4385C>T
gCa/gTa
p.A1462V
0.218
16
4
16
4
AR
X
66765158
66765167
TGCAGCAGCA
T
Deletion
c.171_179del
p.Q78_Q80del
1.0
42
11
42
11
ARHGEF10
8
1857591
1857591
G
A
Missense Variant
c.1984G>A
Gtt/Att
p.V662I
0.508
28
4
28
4
ARHGEF12
11
120340060
120340060
A
T
Missense Variant
c.2861A>T
tAt/tTt
p.Y954F
0.928
13
9
13
9
AXIN1
16
396911
396911
G
A
Missense Variant
c.115C>T
Ccc/Tcc
p.P39S
0.946
5
2
5
2
BCL10
1
85733374
85733374
C
T
Missense Variant
c.605G>A
gGa/gAa
p.G202E
0.283
11
9
11
9
CBFA2T3
16
88951594
88951594
C
T
Missense Variant
c.719G>A
cGc/cAc
p.R240H
0.366
13
2
13
2
CBLC
19
45296806
45296806
C
T
Missense Variant
c.1075C>T
Cac/Tac
p.H359Y
0.43
9
4
9
4
CDH11
16
65016137
65016137
G
C
Missense Variant
c.689C>G
cCg/cGg
p.P230R
0.551
8
2
8
2
CTNND1
11
57564011
57564011
C
T
Missense Variant
c.200C>T
tCa/tTa
p.S67L
0.399
6
1
6
1
DDR2
1
162724986
162724986
A
G
Missense Variant
c.458A>G
aAg/aGg
p.K153R
0.402
9
1
9
1
DDR2
1
162740121
162740121
G
A
Missense Variant
c.1323G>A
atG/atA
p.M441I
0.54
9
5
9
5
EZH2
7
148525904
148525904
C
G
Missense Variant
c.436G>C
Gac/Cac
p.D146H
0.962
11
10
11
10
FANCC
9
97912307
97912307
T
A
Missense Variant
c.584A>T
gAt/gTt
p.D195V
0.91
7
2
7
2
Total mutations showing: 61
F
P
1
2
3
4
5
N
E
Rows Per Page
10
15
25
50
Download
CNV
Histology Information for Model: BCM-15008
Patient
PDX
ER
PR
HER2
Metastasis Information for Model: BCM-15008
Patient
PDX
Abdomen
Anterosuperior mediastinum
Bone
Brain
CTC
Chest
Chest wall
Contralateral breast
Fallopian tubes
Hip
Kidney
Leg bone
Liver
Lung
Lymph Node
Mediastinum
Neck
Other
Ovary
Pancreas
Paratracheal adenopathy
Pericardium
Peritoneal cavity
Peritoneum
Pleura
Pleural Cavitiy
Pleural effusion
Posterior cervical nodes
SVC node
Skin
Thymus
Patient Treatment Information for Model: BCM-15008
Event Id
Treatment
Treatment Setting
Age at Start
Age at End
Duration
Reason Stopped
12
[Doxorubicin, Cyclophosphamide]
Adjuvant
64.1
64.1
Unknown
Side Effects
14
[Docetaxel, Cyclophosphamide]
Adjuvant
64.11
64.45
124 days
Disease Progression
22
[Gemcitabine, Cisplatin]
Recurrent/Metastatic
64.54
64.54
Unknown
Disease Progression
26
[Radiation Therapy (RT), Cisplatin]
Recurrent/Metastatic
64.59
64.65
22 days
Disease Progression
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