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Breast
BCM-15006
Model Details
Patient
PDX Model
Histology
Metastasis
Patient Treatment
Patient Information for Model: BCM-15006
Patient Information
Clinical Timeline
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Negative
N/A
Clinical Information at Collection
Clinical Biomarkers/Mutations at Collection
Pathology Information at Collection
Model Information for Model: BCM-15006
Biomarkers & Mutations
Model Details
Mutations (Cancer Gene Census List)
Download Complete Mutation List
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The number of models in this collection with mutations in the listed gene
The number of models in this collection with mutations at the listed site
Total mutations showing: 88
F
P
1
2
3
4
5
6
N
E
Rows Per Page
10
15
25
50
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Gene
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Chr
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Start
End
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Variant Type
Filter by Variant Type
cDNA Change
Codon Change
Protein Change
TVAF
Gene Mutation Freq.
Site Mutation Freq.
Gene Mutation Freq.
Site Mutation Freq.
ACVR1
2
158622458
158622461
ATTC
A
Deletion
c.1038_1040del
p.K346del
0.231
3
1
3
1
AKAP9
7
91726641
91726644
TAGA
T
Deletion
c.10369_10371del
p.R3458del
0.158
25
2
25
2
ARID1A
1
27023340
27023340
G
A
Missense Variant
c.446G>A
gGc/gAc
p.G149D
0.958
22
2
22
2
ATM
11
108175462
108175462
G
A
Missense Variant
c.5557G>A
Gat/Aat
p.D1853N
1.0
31
12
31
12
BARD1
2
215617178
215617178
C
G
Missense Variant
c.260G>C
tGc/tCc
p.C87S
0.56
18
3
18
3
BIRC6
2
32740544
32740547
ATTC
A
Deletion
c.11057_11059del
p.L3687del
0.158
20
1
20
1
BLM
15
91326099
91326099
C
T
Missense Variant
c.2603C>T
cCg/cTg
p.P868L
0.96
27
8
27
8
BLM
15
91354521
91354521
G
A
Missense Variant
c.3568G>A
Gta/Ata
p.V1190I
1.0
27
11
27
11
CASP9
1
15844718
15844718
G
A
Missense Variant
c.305C>T
aCc/aTc
p.T102I
0.925
17
6
17
6
CDK12
17
37618868
37618871
GAGA
G
Deletion
c.545_547del
p.K183del
1.0
7
2
7
2
CHD2
15
93545488
93545488
T
A
Missense Variant
c.4219T>A
Tct/Act
p.S1407T
0.947
12
2
12
2
CIC
19
42795492
42795492
C
T
Missense Variant
c.2572C>T
Ccc/Tcc
p.P858S
0.977
24
2
24
2
CLIP1
12
122773044
122773044
C
T
Missense Variant
c.3501G>A
atG/atA
p.M1167I
0.2
16
1
16
1
CLIP1
12
122773045
122773045
A
T
Missense Variant
c.3500T>A
aTg/aAg
p.M1167K
0.2
16
1
16
1
CLIP1
12
122773049
122773049
C
T
Missense Variant
c.3496G>A
Gaa/Aaa
p.E1166K
0.2
16
1
16
1
Total mutations showing: 88
F
P
1
2
3
4
5
6
N
E
Rows Per Page
10
15
25
50
Download
CNV
Histology Information for Model: BCM-15006
Patient
PDX
H&E
ER
PR
HER2
Metastasis Information for Model: BCM-15006
Patient
PDX
Abdomen
Anterosuperior mediastinum
Bone
Brain
CTC
Chest
Chest wall
Contralateral breast
Fallopian tubes
Hip
Kidney
Leg bone
Liver
Lung
Lymph Node
Mediastinum
Neck
Other
Ovary
Pancreas
Paratracheal adenopathy
Pericardium
Peritoneal cavity
Peritoneum
Pleura
Pleural Cavitiy
Pleural effusion
Posterior cervical nodes
SVC node
Skin
Thymus
Patient Treatment Information for Model: BCM-15006
Event Id
Treatment
Treatment Setting
Age at Start
Age at End
Duration
Clinical Response
Pathologic Response
Reason Stopped
16
[Doxorubicin, Cyclophosphamide]
Neoadjuvant
33.98
34.09
40 days
Partial Response
Not Reported
Treatment Completed
17
[Paclitaxel, Carboplatin]
Neoadjuvant
34.13
34.34
77 days
Not Reported
Not Reported
Treatment Completed
26
[Radiation Therapy (RT)]
Neoadjuvant
34.39
34.5
40 days
Complete Response
Treatment Completed
27
[Cisplatin]
Neoadjuvant
34.4
34.47
26 days
Complete Response
Treatment Completed
36
[Capecitabine]
Adjuvant
34.8
35.3
183 days
Not Reported
Treatment Completed
38
[Radiation Therapy (RT)]
Recurrent/Metastatic
35.8
0.0
Unknown
Not Reported
Treatment Completed
42
[Capecitabine]
Recurrent/Metastatic
35.83
35.92
33 days
Not Reported
Disease Progression
43
[Eribulin]
Recurrent/Metastatic
35.95
35.96
4 days
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