Model Details

Patient Information for Model: BCM-15006

Patient Information
Clinical Timeline

Color Keys:
 
 Positive
 
 Negative
 
 N/A

Clinical Information at Collection
Clinical Biomarkers/Mutations at Collection
Pathology Information at Collection

Model Information for Model: BCM-15006

Biomarkers & Mutations
Model Details
Mutations (Cancer Gene Census List)

The number of models in this collection with mutations in the listed gene
The number of models in this collection with mutations at the listed site
GeneChrStartEndRefAltVariant TypecDNA ChangeCodon ChangeProtein ChangeTVAF Gene Mutation Freq. Site Mutation Freq.Gene Mutation Freq.Site Mutation Freq.
ACVR12158622458158622461ATTCADeletionc.1038_1040delp.K346del0.2313131
AKAP979172664191726644TAGATDeletionc.10369_10371delp.R3458del0.158252252
ARID1A12702334027023340GAMissense Variantc.446G>AgGc/gAcp.G149D0.958222222
ATM11108175462108175462GAMissense Variantc.5557G>AGat/Aatp.D1853N1.031123112
BARD12215617178215617178CGMissense Variantc.260G>CtGc/tCcp.C87S0.56183183
BIRC623274054432740547ATTCADeletionc.11057_11059delp.L3687del0.158201201
BLM159132609991326099CTMissense Variantc.2603C>TcCg/cTgp.P868L0.96278278
BLM159135452191354521GAMissense Variantc.3568G>AGta/Atap.V1190I1.027112711
CASP911584471815844718GAMissense Variantc.305C>TaCc/aTcp.T102I0.925176176
CDK12173761886837618871GAGAGDeletionc.545_547delp.K183del1.07272
CHD2159354548893545488TAMissense Variantc.4219T>ATct/Actp.S1407T0.947122122
CIC194279549242795492CTMissense Variantc.2572C>TCcc/Tccp.P858S0.977242242
CLIP112122773044122773044CTMissense Variantc.3501G>AatG/atAp.M1167I0.2161161
CLIP112122773045122773045ATMissense Variantc.3500T>AaTg/aAgp.M1167K0.2161161
CLIP112122773049122773049CTMissense Variantc.3496G>AGaa/Aaap.E1166K0.2161161
CNV


Histology Information for Model: BCM-15006

Patient

PDX

H&E

ER

PR

HER2


Metastasis Information for Model: BCM-15006
 
Patient
PDX
Abdomen
Anterosuperior mediastinum
Bone
Brain
CTC
Chest
Chest wall
Contralateral breast
Fallopian tubes
Hip
Kidney
Leg bone
Liver
Lung
Lymph Node
Mediastinum
Neck
Other
Ovary
Pancreas
Paratracheal adenopathy
Pericardium
Peritoneal cavity
Peritoneum
Pleura
Pleural Cavitiy
Pleural effusion
Posterior cervical nodes
SVC node
Skin
Thymus

Patient Treatment Information for Model: BCM-15006

Event IdTreatmentTreatment SettingAge at StartAge at EndDurationClinical ResponsePathologic ResponseReason Stopped
16[Doxorubicin, Cyclophosphamide]Neoadjuvant33.9834.0940 daysPartial ResponseNot ReportedTreatment Completed
17[Paclitaxel, Carboplatin]Neoadjuvant34.1334.3477 daysNot ReportedNot ReportedTreatment Completed
26[Radiation Therapy (RT)]Neoadjuvant34.3934.540 daysComplete ResponseTreatment Completed
27[Cisplatin]Neoadjuvant34.434.4726 daysComplete ResponseTreatment Completed
36[Capecitabine]Adjuvant34.835.3183 daysNot ReportedTreatment Completed
38[Radiation Therapy (RT)]Recurrent/Metastatic35.80.0UnknownNot ReportedTreatment Completed
42[Capecitabine]Recurrent/Metastatic35.8335.9233 daysNot ReportedDisease Progression
43[Eribulin]Recurrent/Metastatic35.9535.964 days












Timeout
Your session is about to expire. Click 'Stay Connected' to continue the session.