Model Details

Patient Information for Model: BCM-15003

Patient Information
Clinical Timeline

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Clinical Information at Collection
Clinical Biomarkers/Mutations at Collection
Pathology Information at Collection

Model Information for Model: BCM-15003

Biomarkers & Mutations
Model Details
Mutations (Cancer Gene Census List)

The number of models in this collection with mutations in the listed gene
The number of models in this collection with mutations at the listed site
GeneChrStartEndRefAltcDNA ChangeCodon ChangeProtein ChangeTVAF Gene Mutation Freq. Site Mutation Freq.Most Severe EffectAll EffectsMutation ImpactTranscript IDClinVar Clinical SignificanceCOSMIC IDgnomAD Non-Cancer AFdbSNP IDGene Mutation Freq.Site Mutation Freq.Transcript IDClinVar Clinical SignificanceCOSMIC IDdbSNP ID
ABL1chr9130878451130878451GTc.1364G>TgGc/gTcp.Gly455Val0.236101Missense Variantmissense_variantMODERATENM_007313.2



101NM_007313.2
ACSL6chr5131945621131945621GC0.94472Downstream Gene Variantdownstream_gene_variantMODIFIERNM_001009185.2


rs908013502
472NM_001009185.2rs908013502
ACSL6chr5132011827132011827GA0.9734724Intragenic Variantintragenic_variantMODIFIER


rs4705908
4724rs4705908
ACSL6chr5132011827132011827GA0.9734724Upstream Gene Variantupstream_gene_variantMODIFIERNM_001009185.2


rs4705908
4724NM_001009185.2rs4705908
AFDNchr6167976539167976540TTGA0.407201Downstream Gene Variantdownstream_gene_variantMODIFIERNM_001291964.1



201NM_001291964.1
AFF1chr48713577387135773AG0.97780803' UTR variant3_prime_UTR_variantMODIFIERNM_001166693.2


rs342464
8080NM_001166693.2rs342464
AFF4chr5132873841132873841TC0.904211Downstream Gene Variantdownstream_gene_variantMODIFIERNM_014423.3


rs1006724642
211NM_014423.3rs1006724642
AKAP9chr79194097691940976GC0.36168645' UTR variant5_prime_UTR_variantMODIFIERNM_005751.4


rs4727267
6864NM_005751.4rs4727267
ALKchr22919315929193163CCATTG0.36840333' UTR variant3_prime_UTR_variantMODIFIERNM_004304.4


rs397706189
4033NM_004304.4rs397706189
APOBEC3Bchr223898211638982116TG0.3622623Upstream Gene Variantupstream_gene_variantMODIFIERNM_004900.4


rs2267401
2623NM_004900.4rs2267401
ARchrX6754531667545316TGCAGCAGCAGCATc.228_239delGCAGCAGCAGCAp.Gln77_Gln80del0.88453In-frame Deletion (Disruptive)disruptive_inframe_deletionMODERATENM_000044.3

COSM4598225
rs781380725
453NM_000044.3COSM4598225rs781380725
ARHGEF10Lchr11769750217697503GGC0.92377773' UTR variant3_prime_UTR_variantMODIFIERNM_018125.3


rs3835471
7777NM_018125.3rs3835471
ASXL1chr203243742832437428TC0.33749433' UTR variant3_prime_UTR_variantMODIFIERNM_015338.5


rs2295763
4943NM_015338.5rs2295763
ATICchr2215311925215311925AG0.9447974Upstream Gene Variantupstream_gene_variantMODIFIERNM_004044.6


rs78631308
7974NM_004044.6rs78631308
ATICchr2215349769215349769TG0.43879613' UTR variant3_prime_UTR_variantMODIFIERNM_004044.6

COSN19749524
rs10498036
7961NM_004044.6COSN19749524rs10498036
CNV


Histology Information for Model: BCM-15003

Patient

PDX

H&E

ER

PR

HER2


Metastasis Information for Model: BCM-15003
 
Patient
PDX
Abdomen
Anterosuperior mediastinum
Bone
Brain
CTC
Chest
Chest wall
Contralateral Breast
Fallopian tubes
Hip
Kidney
Leg bone
Liver
Lung
Lymph Node
Mediastinum
Neck
Other
Ovary
Pancreas
Paratracheal adenopathy
Pericardium
Peritoneal cavity
Peritoneum
Pleura
Pleural Cavitiy
Pleural effusion
Posterior cervical nodes
SVC node
Skin
Thymus

Patient Treatment Information for Model: BCM-15003

Event IdTreatmentTreatment SettingAge at StartAge at EndDuration
12[Docetaxel, Cyclophosphamide]Adjuvant66.6666.8569 days
14[Radiation Therapy (RT)]Adjuvant66.9166.9929 days












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