Model Details

Patient Information for Model: BCM-0113

Patient Information
Clinical Timeline

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Clinical Information at Collection
Clinical Biomarkers/Mutations at Collection
Pathology Information at Collection

Model Information for Model: BCM-0113

Biomarkers & Mutations
Model Details
Mutations (Cancer Gene Census List)

The number of models in this collection with mutations in the listed gene
The number of models in this collection with mutations at the listed site
GeneChrStartEndRefAltVariant TypecDNA ChangeCodon ChangeProtein ChangeTVAF Gene Mutation Freq. Site Mutation Freq.Gene Mutation Freq.Site Mutation Freq.
AFF32100210334100210335CGCFrame-shift Deletionc.1863delCp.D623Tfs*470.407174174
AFF32100210337100210342CTGAGGCFrame-shift Deletionc.1856_1860delp.T619Sfs*710.429174174
AKAP979173502391735023GCMissense Variantc.11362G>CGtc/Ctcp.V3788L0.444251251
ANK184155280941552809GAMissense Variantc.3001C>TCgt/Tgtp.R1001C0.207161161
ARX6676515866765164TGCAGCATDeletionc.171_176delp.Q79_Q80del1.0427427
ATM11108117798108117798CTMissense Variantc.1009C>TCgt/Tgtp.R337C0.387311311
BCL1018573337485733374CTMissense Variantc.605G>AgGa/gAap.G202E1.0119119
BCL7A12122481879122481879ACMissense Variantc.359A>CaAc/aCcp.N120T0.5373232
BRCA1174124350941243509TCMissense Variantc.3898A>GAga/Ggap.R1300G0.579251251
CBLB3105421060105421060CAMissense Variantc.1690G>TGgc/Tgcp.G564C0.3397171
CEP89193337281433372814GAMissense Variantc.2071C>TCgg/Tggp.R691W0.9949696
CIC194279500642795006CTMissense Variantc.2086C>TCgg/Tggp.R696W0.455241241
CIC194279929442799294AAGFrame-shift Insertionc.4779dupGp.P1594Afs*190.211241241
CIC194279929942799299TCMissense Variantc.4783T>CTcc/Cccp.S1595P0.174247247
CLIP112122817580122817580AGMissense Variantc.2683T>CTct/Cctp.S895P0.577166166
CNV


Histology Information for Model: BCM-0113

Patient

PDX

H&E

ER

PR

HER2


Metastasis Information for Model: BCM-0113
 
Patient
PDX
Abdomen
Anterosuperior mediastinum
Bone
Brain
CTC
Chest
Chest wall
Contralateral breast
Fallopian tubes
Hip
Kidney
Leg bone
Liver
Lung
Lymph Node
Mediastinum
Neck
Other
Ovary
Pancreas
Paratracheal adenopathy
Pericardium
Peritoneal cavity
Peritoneum
Pleura
Pleural Cavitiy
Pleural effusion
Posterior cervical nodes
SVC node
Skin
Thymus

Patient Treatment Information for Model: BCM-0113

Event IdTreatmentTreatment SettingAge at StartAge at EndDurationClinical ResponsePathologic ResponseReason Stopped
6[Doxorubicin]Neoadjuvant63.5163.5826 daysNot ReportedNot ReportedUnknown
8[Doxorubicin, Cyclophosphamide]Neoadjuvant63.6663.8362 daysNot ReportedNot ReportedTreatment Completed
12[Docetaxel]Neoadjuvant63.8963.89UnknownNot ReportedNot ReportedSide Effects
14[Paclitaxel]Neoadjuvant63.9564.0329 daysNot ReportedNot ReportedSide Effects
17[Carboplatin]Adjuvant64.2164.3862 daysNot ReportedNot ReportedTreatment Completed
32[Ixabepilone, Capecitabine]Recurrent/Metastatic64.5364.7373 daysNot ReportedNot ReportedUnknown












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