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Model Details

Patient Information for Model: BCM-0104

Patient Information

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Clinical Information at Collection

Clinical Biomarkers/Mutations at Collection

Pathology Information at Collection

Model Information for Model: BCM-0104

Biomarkers & Mutations

Model Details

Mutations

GeneFilter by Gene	ChrFilter by Chr	Start	End	Ref	Alt	Variant TypeFilter by Variant Type	cDNA Change	Codon Change	Protein Change	TVAF	Gene Mutation Freq.	Site Mutation Freq.
AC091801.1	7	3188683	3188683	C	T	Missense Variant	c.112G>A	c.(112-114)Gcc>Acc	p.A38T	0.444	1	1
AC136604.1	5	179078817	179078940	CCAGGCATCAGAGCCTCTGTGTCCCCTGAAGCACCCTTCACACCGGCCACCTGCGAGCACCCTATCACCAAACCTGACCAGCTCCACAGAATCCTTGGGGTATCTGTCATCCCTCAGCTCCTCT	C	In-frame Deletion	c.301_423delCAGGCATCAGAGCCTCTGTGTCCCCTGAAGCACCCTTCACACCGGCCACCTGCGAGCACCCTATCACCAAACCTGACCAGCTCCACAGAATCCTTGGGGTATCTGTCATCCCTCAGCTCCTCT	c.(301-423)caggcatcagagcctctgtgtcccctgaagcacccttcacaccggccacctgcgagcaccctatcaccaaacctgaccagctccacagaatccttggggtatctgtcatccctcagctcctctdel	p.QASEPLCPLKHPSHRPPASTLSPNLTSSTESLGYLSSLSSS101del	0.34	1	1
AC136604.1	5	179078992	179078992	G	GGGC	In-frame Insertion	c.475_475insGGC	c.(475-477)ggg>GGCggg	p.159_159G>GG	0.446	1	1
ACAN	15	89400023	89400023	A	G	Missense Variant	c.4207A>G	c.(4207-4209)Act>Gct	p.T1403A	0.956	20	15
ACE	17	61566422	61566422	G	A	Missense Variant	c.848G>A	c.(847-849)cGc>cAc	p.R283H	0.994	4	1
ADAMTS14	10	72511851	72511851	G	C	Splice Site	c.2606G>C	c.(2605-2607)gGg>gCg	p.G869A	0.608	2	1
ADARB1	21	46600320	46600320	G	A	Missense Variant	c.1039G>A	c.(1039-1041)Gct>Act	p.A347T	0.306	2	1
AFF3	2	100623675	100623675	C	T	Missense Variant	c.422G>A	c.(421-423)aGt>aAt	p.S141N	0.69	5	1
ANK3	10	61832685	61832685	G	A	Missense Variant	c.7954C>T	c.(7954-7956)Cat>Tat	p.H2652Y	0.74	7	1
APTX	9	32974473	32974473	T	C	Missense Variant	c.899A>G	c.(898-900)tAc>tGc	p.Y300C	0.508	2	1
ARHGAP26	5	142593647	142593647	G	A	Missense Variant	c.2350G>A	c.(2350-2352)Gat>Aat	p.D784N	1.0	2	1
ATXN1	6	16327915	16327915	ATGC	ATGCTGC	In-frame Insertion	c.627_627insGCAGCA	c.(625-627)cat>caGCAGCAt	p.208_209insQQ	0.605	36	32
C1QTNF8	16	1144910	1144910	C	T	Missense Variant	c.13G>A	c.(13-15)Gcc>Acc	p.A5T	1.0	1	1
CAC1S	1	201009194	201009194	C	T	Missense Variant	c.5387G>A	c.(5386-5388)gGc>gAc	p.G1796D	0.827	7	1
CACYBP	1	174977840	174977844	AGAGT	A	Deletion at Splice Site	c.400_401delGAGT	c.(400-402)gag>g	p.E134fs	0.475	1	1

CNV

Histology Information for Model: BCM-0104

Patient

PDX

H&E

ER

PR

HER2

Metastasis Information for Model: BCM-0104

Patient

PDX

Abdomen

Anterosuperior mediastinum

Bone

Brain

CTC

Chest

Chest wall

Contralateral breast

Fallopian tubes

Hip

Kidney

Leg bone

Liver

Lung

Lymph Node

Mediastinum

Neck

Other

Ovary

Pancreas

Paratracheal adenopathy

Pericardium

Peritoneal cavity

Peritoneum

Pleura

Pleural Cavitiy

Pleural effusion

Posterior cervical nodes

SVC node

Skin

Thymus

Patient Treatment Information for Model: BCM-0104

Event Id	Treatment	Treatment Setting	Age at Start	Age at End	Duration	Clinical Response	Pathologic Response
13	[Paclitaxel]	Neoadjuvant	58.3	58.76	168 days	Partial Response	Not Reported
23	[Radiation Therapy (RT)]	Adjuvant	59.33	59.46	47 days	Not Reported	Not Applicable
33	[Radiation Therapy (RT)]	Recurrent/Metastatic	59.81	59.84	11 days	Not Reported	Not Applicable