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Model Details

Patient Information for Model: BCM-0104

Patient Information

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Clinical Information at Collection

Clinical Biomarkers/Mutations at Collection

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Model Information for Model: BCM-0104

Biomarkers & Mutations

Model Details

Mutations (Cancer Gene Census List)

GeneFilter by Gene	ChrFilter by Chr	Start	End	Ref	Alt	cDNA Change	Codon Change	Protein Change	TVAF	Gene Mutation Freq.	Site Mutation Freq.	Most Severe Effect	All Effects	Mutation Impact	Transcript ID	COSMIC ID	gnomAD Non-Cancer AF	dbSNP ID	Gene Mutation Freq.	Site Mutation Freq.	Transcript ID	COSMIC ID	dbSNP ID
ABI1	chr10	26742285	26742285	A	G				0.799	40	34	Downstream Gene Variant	downstream_gene_variant	MODIFIER	NM_005470.3			rs10764638	40	34	NM_005470.3		rs10764638
ACSL6	chr5	132011827	132011827	G	A				0.947	47	24	Upstream Gene Variant	upstream_gene_variant	MODIFIER	NM_001009185.2			rs4705908	47	24	NM_001009185.2		rs4705908
ACSL6	chr5	132011827	132011827	G	A				0.947	47	24	Intragenic Variant	intragenic_variant	MODIFIER				rs4705908	47	24			rs4705908
AFF1	chr4	87135773	87135773	A	G				0.934	80	80	3' UTR variant	3_prime_UTR_variant	MODIFIER	NM_001166693.2			rs342464	80	80	NM_001166693.2		rs342464
AFF3	chr2	100007213	100007213	C	T	c.497G>A	aGt/aAt	p.Ser166Asn	0.671	10	1	Missense Variant	missense_variant	MODERATE	NM_001025108.1		0.000004220760	rs151087811	10	1	NM_001025108.1		rs151087811
AFF4	chr5	132873544	132873544	G	A				0.906	21	1	Downstream Gene Variant	downstream_gene_variant	MODIFIER	NM_014423.3			rs576657215	21	1	NM_014423.3		rs576657215
AKAP9	chr7	91940976	91940976	G	C				0.97	68	64	5' UTR variant	5_prime_UTR_variant	MODIFIER	NM_005751.4			rs4727267	68	64	NM_005751.4		rs4727267
AR	chrX	67545316	67545316	TGCA	T	c.237_239delGCA		p.Gln80del	0.638	45	8	In-frame Deletion (Disruptive)	disruptive_inframe_deletion	MODERATE	NM_000044.3			rs778920072	45	8	NM_000044.3		rs778920072
ARHGAP26	chr5	143214082	143214082	G	A	c.2350G>A	Gat/Aat	p.Asp784Asn	0.889	3	1	Missense Variant	missense_variant	MODERATE	NM_015071.4		0.000005067700	rs587778049	3	1	NM_015071.4		rs587778049
ARHGEF10L	chr1	17697502	17697503	G	GC				0.958	77	77	3' UTR variant	3_prime_UTR_variant	MODIFIER	NM_018125.3			rs3835471	77	77	NM_018125.3		rs3835471
ATIC	chr2	215311925	215311925	A	G				0.999	79	74	Upstream Gene Variant	upstream_gene_variant	MODIFIER	NM_004044.6			rs78631308	79	74	NM_004044.6		rs78631308
ATIC	chr2	215312084	215312084	T	G				0.998	79	23	5' UTR variant	5_prime_UTR_variant	MODIFIER	NM_004044.6			rs4535042	79	23	NM_004044.6		rs4535042
ATRX	chrX	77682471	77682471	C	G	c.2785G>C	Gag/Cag	p.Glu929Gln	0.563	54	52	Missense Variant	missense_variant	MODERATE	NM_000489.4			rs3088074	54	52	NM_000489.4		rs3088074
B2M	chr15	44711166	44711166	T	G				0.999	48	45	Upstream Gene Variant	upstream_gene_variant	MODIFIER	NM_004048.2	COSN15632065		rs2255235	48	45	NM_004048.2	COSN15632065	rs2255235
BAP1	chr3	52397655	52397655	G	A				0.999	22	8	Downstream Gene Variant	downstream_gene_variant	MODIFIER	NM_004656.3			rs390802	22	8	NM_004656.3		rs390802

CNV

Histology Information for Model: BCM-0104

Patient

PDX

H&E

ER

PR

HER2

Metastasis Information for Model: BCM-0104

Patient

PDX

Abdomen

Anterosuperior mediastinum

Bone

Brain

CTC

Chest

Chest wall

Contralateral breast

Fallopian tubes

Hip

Kidney

Leg bone

Liver

Lung

Lymph Node

Mediastinum

Neck

Other

Ovary

Pancreas

Paratracheal adenopathy

Pericardium

Peritoneal cavity

Peritoneum

Pleura

Pleural Cavitiy

Pleural effusion

Posterior cervical nodes

SVC node

Skin

Thymus

Patient Treatment Information for Model: BCM-0104

Event Id	Treatment	Treatment Setting	Age at Start	Age at End	Duration	Clinical Response	Pathologic Response
13	[Paclitaxel]	Neoadjuvant	58.3	58.76	168 days	Partial Response	Not Reported
23	[Radiation Therapy (RT)]	Adjuvant	59.33	59.46	47 days	Not Reported	Not Applicable
33	[Radiation Therapy (RT)]	Recurrent/Metastatic	59.81	59.84	11 days	Not Reported	Not Applicable