Model Details

Patient Information for Model: BCM-0104

Patient Information
Clinical Timeline

Color Keys:
 
 Positive
 
 Negative
 
 N/A

Clinical Information at Collection
Clinical Biomarkers/Mutations at Collection
Pathology Information at Collection

Model Information for Model: BCM-0104

Biomarkers & Mutations
Model Details
Mutations (Cancer Gene Census List)

The number of models in this collection with mutations in the listed gene
The number of models in this collection with mutations at the listed site
GeneChrStartEndRefAltVariant TypecDNA ChangeCodon ChangeProtein ChangeTVAF Gene Mutation Freq. Site Mutation Freq.Gene Mutation Freq.Site Mutation Freq.
AFF32100623675100623675CTMissense Variantc.497G>AaGt/aAtp.S166N0.69171171
AKAP979170889891708898AGMissense Variantc.7451A>GaAa/aGap.K2484R1.0259259
ARHGAP265142593647142593647GAMissense Variantc.1966G>AGat/Aatp.D656N1.02121
ARHGEF10818767071876707GAMissense Variantc.2698G>AGtt/Attp.V900I1.0282282
ARID1A12702397127023971CAMissense Variantc.1077C>AcaC/caAp.H359Q0.4221221
ATR3142178144142178144CTMissense Variantc.7274G>AcGa/cAap.R2425Q0.43930163016
CIC194279929942799299TCMissense Variantc.4783T>CTcc/Cccp.S1595P0.125247247
CYP2C8109679874996798749TCMissense Variantc.890A>GaAa/aGap.K297R0.69634163416
CYP2C8109682703096827030CTMissense Variantc.110G>AaGg/aAgp.R37K0.64934163416
EGFR75522925555229255GAMissense Variantc.761G>AaGg/aAgp.R254K0.32839253925
ELF31201981774201981774GAMissense Variantc.485G>AgGc/gAcp.G162D0.35110101010
ERCC2194586725945867259CTMissense Variantc.862G>AGac/Aacp.D288N1.039373937
ERCC4161402903314029033GAMissense Variantc.1244G>AcGa/cAap.R415Q1.0136136
ETV53185798862185798862TCMissense Variantc.335A>GtAt/tGtp.Y112C0.5317171
FANCA168988300789883007ATMissense Variantc.17T>AgTc/gAcp.V6D1.0426426
CNV


Histology Information for Model: BCM-0104

Patient

PDX

H&E

ER

PR

HER2


Metastasis Information for Model: BCM-0104
 
Patient
PDX
Abdomen
Anterosuperior mediastinum
Bone
Brain
CTC
Chest
Chest wall
Contralateral breast
Fallopian tubes
Hip
Kidney
Leg bone
Liver
Lung
Lymph Node
Mediastinum
Neck
Other
Ovary
Pancreas
Paratracheal adenopathy
Pericardium
Peritoneal cavity
Peritoneum
Pleura
Pleural Cavitiy
Pleural effusion
Posterior cervical nodes
SVC node
Skin
Thymus

Patient Treatment Information for Model: BCM-0104

Event IdTreatmentTreatment SettingAge at StartAge at EndDurationClinical ResponsePathologic Response
13[Paclitaxel]Neoadjuvant58.358.76168 daysPartial ResponseNot Reported
23[Radiation Therapy (RT)]Adjuvant59.3359.4647 daysNot ReportedNot Applicable
33[Radiation Therapy (RT)]Recurrent/Metastatic59.8159.8411 daysNot ReportedNot Applicable












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