Model Details

Patient Information for Model: BCM-0046

Patient Information
Clinical Timeline

Color Keys:
 
 Positive
 
 Negative
 
 N/A

Clinical Information at Collection
Clinical Biomarkers/Mutations at Collection
Pathology Information at Collection

Model Information for Model: BCM-0046

Biomarkers & Mutations
Model Details
Mutations (Cancer Gene Census List)

The number of models in this collection with mutations in the listed gene
The number of models in this collection with mutations at the listed site
GeneChrStartEndRefAltVariant TypecDNA ChangeCodon ChangeProtein ChangeTVAF Gene Mutation Freq. Site Mutation Freq.Gene Mutation Freq.Site Mutation Freq.
ALDH212112227649112227649ATNonsense Mutationc.322A>TAag/Tagp.K108*0.7731111
ASPSCR1177997472479974724CTMissense Variantc.1298C>TgCg/gTgp.A433V1.05252
BAP135243851652438516ACNonsense Mutationc.1203T>GtaT/taGp.Y401*1.06161
BAP135243851852438518ACMissense Variantc.1201T>GTat/Gatp.Y401D1.06161
BAZ1A143523098035230980CTMissense Variantc.4130G>AaGa/aAap.R1377K0.154256256
BAZ1A143523110835231108ATMissense Variantc.4002T>AaaT/aaAp.N1334K0.239256256
BAZ1A143526198835261988GTMissense Variantc.1503C>AgaC/gaAp.D501E0.385251251
BAZ1A143526947635269476ATMissense Variantc.1082T>AcTa/cAap.L361Q0.25251251
BAZ1A143526947735269477GTMissense Variantc.1081C>ACta/Atap.L361I0.25251251
BAZ1A143526947935269479CTMissense Variantc.1079G>AaGa/aAap.R360K0.25251251
CCR7173871518638715186TCMissense Variantc.1A>GAtg/Gtgp.M1V1.03232
CHD2159355795493557954GCMissense Variantc.4721G>CgGg/gCgp.G1574A0.5128128
CLTCL1221918378719183787AGMissense Variantc.4181T>CaTc/aCcp.I1394T1.0375375
CLTCL1221919794919197949GAMissense Variantc.3136C>TCgc/Tgcp.R1046C1.0375375
CLTCL1221919568019195680TCMissense Variantc.3584A>GaAt/aGtp.N1195S1.0375375
CNV


Histology Information for Model: BCM-0046

Patient

PDX

H&E

ER

PR

HER2


Metastasis Information for Model: BCM-0046
 
Patient
PDX
Abdomen
Anterosuperior mediastinum
Bone
Brain
CTC
Chest
Chest wall
Contralateral breast
Fallopian tubes
Hip
Kidney
Leg bone
Liver
Lung
Lymph Node
Mediastinum
Neck
Other
Ovary
Pancreas
Paratracheal adenopathy
Pericardium
Peritoneal cavity
Peritoneum
Pleura
Pleural Cavitiy
Pleural effusion
Posterior cervical nodes
SVC node
Skin
Thymus

Patient Treatment Information for Model: BCM-0046

Event IdTreatmentTreatment SettingAge at StartAge at EndDurationClinical ResponsePathologic Response
8[Epirubicin, Cyclophosphamide]Neoadjuvant53.6253.8480 daysPartial ResponseNot Reported
12[Docetaxel]Neoadjuvant53.8554.0262 daysNot ReportedNot Reported
22[Radiation Therapy (RT)]Adjuvant54.2454.4162 daysNot ReportedNot Reported












Timeout
Your session is about to expire. Click 'Stay Connected' to continue the session.