Model Details

Patient Information for Model: BCM-0002

Patient Information
Clinical Timeline

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Clinical Information at Collection
Clinical Biomarkers/Mutations at Collection
Pathology Information at Collection

Model Information for Model: BCM-0002

Biomarkers & Mutations
Model Details
Mutations
The number of models in this collection with mutations in the listed gene
The number of models in this collection with mutations at the listed site
GeneChrStartEndRefAltVariant TypecDNA ChangeCodon ChangeProtein ChangeTVAFCOSMIC ID Gene Mutation Freq. Site Mutation Freq.
A2M1292460659246065CGMissense Variantc.2236G>Cc.(2236-2238)Gta>Ctap.V746L1.0COSM637963921
AATK177909441779094417GCMissense Variantc.3319C>Gc.(3319-3321)Ccg>Gcgp.P1107A0.11781
ABCA19107568539107568539CGMissense Variantc.4447G>Cc.(4447-4449)Ggg>Cggp.G1483R0.35331
ABCA10176718995967189959TAMissense Variantc.1517A>Tc.(1516-1518)cAa>cTap.Q506L0.32721
ABCC11164822087748220877CGMissense Variantc.3058G>Cc.(3058-3060)Gac>Cacp.D1020H0.47131
ACAN158940035989400359CGMissense Variantc.4543C>Gc.(4543-4545)Cta>Gtap.L1515V0.16201
ACAN158940002389400023AGMissense Variantc.4207A>Gc.(4207-4209)Act>Gctp.T1403A0.7692015
ACHE7100489967100489967ATMissense Variantc.1541T>Ac.(1540-1542)tTt>tAtp.F514Y0.15511
ACRBP1267481386748138CGMissense Variantc.1491G>Cc.(1489-1491)atG>atCp.M497I0.443COSM552617531
ADAMTS811130297719130297719GAMissense Variantc.463C>Tc.(463-465)Ccc>Tccp.P155S0.34531
ADH1A4100208773100208773GTMissense Variantc.68C>Ac.(67-69)tCc>tAcp.S23Y0.43511
ADK107628513576285135CTMissense Variantc.677C>Tc.(676-678)tCa>tTap.S226L0.55821
AFM47435008874350088CAMissense Variantc.251C>Ac.(250-252)cCa>cAap.P84Q0.17611
AGO28141549480141549480GCMissense Variantc.2108C>Gc.(2107-2109)aCc>aGcp.T703S0.15521
AGPAT5865662126566212AGMissense Variantc.23A>Gc.(22-24)cAc>cGcp.H8R1.011
CNV


Histology Information for Model: BCM-0002

Patient

PDX

H&E

ER

PR

HER2


Metastasis Information for Model: BCM-0002
 
Patient
PDX
Abdomen
Anterosuperior mediastinum
Bone
Brain
CTC
Chest
Chest wall
Contralateral breast
Fallopian tubes
Hip
Kidney
Leg bone
Liver
Lung
Lymph Node
Mediastinum
Neck
Other
Ovary
Pancreas
Paratracheal adenopathy
Pericardium
Peritoneal cavity
Peritoneum
Pleura
Pleural Cavitiy
Pleural effusion
Posterior cervical nodes
SVC node
Skin
Thymus

Patient Treatment Information for Model: BCM-0002

Event IdTreatmentTreatment SettingAge at StartAge at EndDurationClinical ResponsePathologic Response
30[Paclitaxel, Carboplatin]Recurrent/Metastatic52.5754.24610 daysStable DiseaseNot Reported
32[Carboplatin]Recurrent/Metastatic54.2454.91245 daysNot ReportedNot Reported
36[Exemestane]Recurrent/Metastatic55.055.65237 daysNot ReportedNot Reported
37[Anastrozole]Recurrent/Metastatic55.650.0UnknownNot ReportedNot Reported
41[Capecitabine]Recurrent/Metastatic56.1257.05339 daysProgressive DiseaseNot Reported
45[Gemcitabine]Recurrent/Metastatic57.0557.1329 daysStable DiseaseNot Reported
47[Gemcitabine]Recurrent/Metastatic57.950.0UnknownNot ReportedNot Reported
[Tamoxifen, Letrozole]Adjuvant0.00.0UnknownNot ReportedNot Reported
[Docetaxel, Doxorubicin]Neoadjuvant0.00.0UnknownNot ReportedNot Reported
[Radiation Therapy (RT)]Adjuvant0.00.0UnknownNot ReportedNot Reported












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