Model Details

Patient Information for Model: BCM-0002

Patient Information
Clinical Timeline

Color Keys:
 
 Positive
 
 Negative
 
 N/A

Clinical Information at Collection
Clinical Biomarkers/Mutations at Collection
Pathology Information at Collection

Model Information for Model: BCM-0002

Biomarkers & Mutations
Model Details
Mutations (Cancer Gene Census List)

The number of models in this collection with mutations in the listed gene
The number of models in this collection with mutations at the listed site
GeneChrStartEndRefAltVariant TypecDNA ChangeCodon ChangeProtein ChangeTVAF Gene Mutation Freq. Site Mutation Freq.Gene Mutation Freq.Site Mutation Freq.
A1CF105256661152566611CTMissense Variantc.1639G>AGtg/Atgp.V547M0.5297575
AKAP979170703591707035CTMissense Variantc.6791C>TgCc/gTcp.A2264V0.098251251
ALK22941664729416650GCTCGDeletionc.4303_4305delp.E1435del0.332172172
APC5112043495112043537CGGCGGCAGCAGGAGCTGCGTCCGGCAGGAGACGAAGAGCCCGCDeletionc.82_123delp.S30_G43del0.3338181
APOBEC3B223938208139382081AGMissense Variantc.439A>GAtc/Gtcp.I147V1.07171
ARX6676515866765173TGCAGCAGCAGCAGCATDeletionc.171_185delp.Q76_Q80del1.0423423
ARID1B6157099402157099402CCCAGInsertionc.339_340insCAGp.Q131_H132insQ1.0372372
BCL1018573337485733374CTMissense Variantc.605G>AgGa/gAap.G202E0.462119119
BCL91147091662147091665CATGCDeletionc.1702_1704delp.M568del0.286111111
CASP911582044815820448GTMissense Variantc.647C>AaCc/aAcp.T216N0.188176176
CDH11166503270865032708CTMissense Variantc.280G>AGgg/Aggp.G94R0.5198181
CLTCL1221921381619213816GANonsense Mutationc.1873C>TCaa/Taap.Q625*0.987371371
CNTRL9123888144123888144GTMissense Variantc.299G>TaGa/aTap.R100I0.281321321
CREB3L1114634228346342283TGMissense Variantc.1547T>GaTc/aGcp.I516S0.511226226
DDR21162741822162741822GAMissense Variantc.1513G>AGgt/Agtp.G505S0.2369191
CNV


Histology Information for Model: BCM-0002

Patient

PDX

H&E

ER

PR

HER2


Metastasis Information for Model: BCM-0002
 
Patient
PDX
Abdomen
Anterosuperior mediastinum
Bone
Brain
CTC
Chest
Chest wall
Contralateral breast
Fallopian tubes
Hip
Kidney
Leg bone
Liver
Lung
Lymph Node
Mediastinum
Neck
Other
Ovary
Pancreas
Paratracheal adenopathy
Pericardium
Peritoneal cavity
Peritoneum
Pleura
Pleural Cavitiy
Pleural effusion
Posterior cervical nodes
SVC node
Skin
Thymus

Patient Treatment Information for Model: BCM-0002

Event IdTreatmentTreatment SettingAge at StartAge at EndDurationClinical ResponsePathologic Response
30[Paclitaxel, Carboplatin]Recurrent/Metastatic52.5754.24610 daysStable DiseaseNot Reported
32[Carboplatin]Recurrent/Metastatic54.2454.91245 daysNot ReportedNot Reported
36[Exemestane]Recurrent/Metastatic55.055.65237 daysNot ReportedNot Reported
37[Anastrozole]Recurrent/Metastatic55.650.0UnknownNot ReportedNot Reported
41[Capecitabine]Recurrent/Metastatic56.1257.05339 daysProgressive DiseaseNot Reported
45[Gemcitabine]Recurrent/Metastatic57.0557.1329 daysStable DiseaseNot Reported
47[Gemcitabine]Recurrent/Metastatic57.950.0UnknownNot ReportedNot Reported
[Tamoxifen, Letrozole]Adjuvant0.00.0UnknownNot ReportedNot Reported
[Docetaxel, Doxorubicin]Neoadjuvant0.00.0UnknownNot ReportedNot Reported
[Radiation Therapy (RT)]Adjuvant0.00.0UnknownNot ReportedNot Reported












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