Leukemia Collection


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  • TCH
Patients (9)
PDX (10)


Collection Summaries:
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Model IDPatient IDPathology Diagnosis
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Age at Diagnosis
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Clinical Event PointWBC
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Patient Molecular FeaturesComplete ISCNFlow BlastPatient Treatment
TCH-AML001AML001Acute myeloid leukemiaWhite1.33MaleDiagnosis4052000No3Not Reported47,XY,+8[20].ish ins(10;11)(p1?3;q23q23)(10pter+,wcp10+,wcp11+,5'MLL+;wcp11+, 5'MLL-,3'MLL+,11qter+)902CDA,AAML1031 ADE10,ADE8,AE,Erwinia,HDAC,Ida,MTX,Multiple intensive regimens,PEG-asp,VCR,dexamethasone
TCH-AML002AML002Acute myeloid leukemiaBlack or African American20.04FemaleRefractoryUnknownUnknownNoUnknownNot Reportedt(7;21), -17Not ReportedCytarabine,Fludarabine,Idarubicin,azacitidine,clo,decitabine,thiotepa,topotecan,venetoclax,venetoclax then DLI,vinorelbine
TCH-AML003AML003T-Acute myeloid leukemiaWhite,Hispanic or Latino7.12MaleDiagnosis630No2FLT3 Alteration46,XY,t(11;19)(q23;p13.1)[20]80FLAG,TVTC,Vyxeos,decitabine,vorinostat
TCH-AML004AML004Acute myeloid leukemiaWhite,Hispanic or Latino1.16MaleDiagnosis114502No1IDH246,XY,der(21)t(1;21)(q25;q22)[9]/46,XY[11]25ADE10,ADE8,Decitabine,Enasidanib,FLAG,Vorino,Vyxeos
TCH-AML005aAML005Acute myeloid leukemiaWhite,Hispanic or Latino16.7MaleDiagnosis3484804No3RAS pathway47,XY,del(11)(q23q25),+21[20]; t(6;11)97ADE10,Azacitidine,Cytarabine,Decitabine,FLAG,Flud,Stem Cell Transplant,Vorino,azacitidine,venetoclax
TCH-AML005bAML005Acute myeloid leukemiaWhite,Hispanic or Latino16.7MaleResidual Disease3484804No3RAS pathway47,XY,del(11)(q23q25),+21[20]; t(6;11)97ADE10,Azacitidine,Cytarabine,Decitabine,FLAG,Flud,Stem Cell Transplant,Vorino,azacitidine,venetoclax
TCH-AML006AML006Acute myeloid leukemiaBlack or African American9.7MaleRefractory716001.5No2WT1,RAS Pathway46,XY,t(1;6;11)(q21;q27;q23)[19]/46,XY[1]652CDA,ADE10 + GO,ADE8,Idarubicin,asparaginase,cytarabine,etoposide,mitoxantrone
TCH-AML008AML008Acute myeloid leukemiaWhite3.0FemaleDiagnosis699700No3NUP98-KDM5A,RAD2146,X, dup(X)(q23q21)62ADE10,ADE8,FLAG,cytarabine,etoposide
TCH-AML010AML010Acute myeloid leukemiaWhite,Hispanic or Latino2.54MaleDiagnosis678000No1WT147, XY, +1054ADE10,ADE8,asparaginase,cytarabine,etoposide,mitoxantrone
TCH-AML011AML011Acute myeloid leukemiaWhite19.72FemaleDiagnosis397000.7No2FLT3 ITD or ALM,CEBPa or NPM1,WT146, XX89ADE10 + sorafenib,ADE8 + sorafenib,Stem cell transplant,cytarabine,etoposide + sorafenib
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